Webunc-13 homolog A (C. elegans) Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential ... This gene encodes a member of the UNC13 family. UNC13A plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity … See more Unc-13 homolog A (C. elegans) is a protein that in humans is encoded by the UNC13A gene. See more Several conserved domains have been found in UNC13A. These conserved domains include three C2 domains. One C2 domain is … See more UNC13A has been shown to interact with: • STX1A, • STX1B1, • DOC2A, • BSN, See more • Augustin I, Rosenmund C, Südhof TC, Brose N (July 1999). "Munc13-1 is essential for fusion competence of glutamatergic … See more UNC13A is localized to the active zone of presynaptic density. It is translocated to the plasma membrane in response to phorbol ester See more Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis. This single nucleotide polymorphism has been discovered on chromosome 19. This variation of the single nucleotide involving UNC13A has also … See more
Drosophila UNC-13 is essential for synaptic transmission.
Web21 Mar 2024 · UNC13A (Unc-13 Homolog A) is a Protein Coding gene. Diseases associated with UNC13A include Amyotrophic Lateral Sclerosis 1 and Lateral Sclerosis . Among its … http://www.informatics.jax.org/marker/MGI:3051532 geforce 605 最大分辨率
UniProt
WebUNC13A, Munc13-1 Associated Syndromes - Chromosome Band 19p13.11 Associated Disorders - Relevance to Autism A de novo missense variant in the UNC13A gene (p.Pro814Leu) was identified in a 6-year-old diagnosed with ASD and comorbid ADHD and presenting with developmental delay and a dyskinetic movement disorder in Lipstein et … WebYour source for quantitative metabolomics technologies and bioinformatics. HMDB0007170 (DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0)) Protein Associations Web26 Oct 2024 · This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at … dcf 計算式 wacc