Histone chaperone hira
WebbHistone. Schematic representation of the assembly of the core histones into the nucleosome. In biology, histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic … Webb6 aug. 2024 · The presence of the Histone regulator A (HIRA) with the histone variant H3.3 in a soluble complex has implicated this histone chaperone in the specific deposition …
Histone chaperone hira
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WebbHistone chaperone HIRA orchestrates dynamic chromatin in senescent cells and is required for suppression of oncogene-induced neoplasia ... Genes Dev Dec 2014 Other authors. See publication. Identification and characterization of novel histone modifications during cellular senescence (Doctoral dissertation, University of Glasgow). Mar 2014 Webb1 mars 2016 · HIRA is the histone chaperone responsible for replication-independent incorporation of H3.3 at genic regions. In contrast, H3.3 incorporation at most regulatory …
WebbHira is the main H3.3 chaperone that governs this protamine-to-histone exchange. In this study, we investigated the maternal functions of two other molecules of the Hira … Webb22 mars 2024 · Our data supports and corroborates conclusions drawn by Rai et al., which identified HIRA to play an important role in the intrinsic antiviral restriction of ΔICP0 …
WebbCROSS-REFERENCE TO RELATED APPLICATIONS. This application is a Continuation of U.S. patent application Ser. No. 16/649,732, filed Mar. 23, 2024, which is a national stage filing u Webb2 sep. 2014 · Further supporting these observations, the biochemical isolation and characterization of protein complexes containing preassembled histone H3.1 and H3.3 …
Webb14 apr. 2024 · Loss of HISTONE REGULATOR A (HIRA), a histone chaperone responsible for H3.3 deposition, reduces cellular H3 levels and increases chromatin …
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