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WebWebMD - Better information. Better health. WebCyclobenzaprine Interactions. There are 400 drugs known to interact with cyclobenzaprine, along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 89 are major, 306 are moderate, and 5 are minor. These classifications are only a guideline. The relevance of a particular drug inter… Cyclobenzaprine has anticholinergic activity, to which elderly patients are particul… Flexeril (cyclobenzaprine) for Muscle Spasm "I find Flexeril 'tops' for killing muscl… There is 1 alcohol/food/lifestyle interaction with cyclobenzaprine. Moderate cyclo… WebModerate Interactions. These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. SLT MODERATE AND WEAK ... neral matheran train timing