WebDec 4, 2024 · BTG3 is a direct downstream target of miR-106b-5p. BTG3 overexpression inhibited tumor growth of SW620 cells by suppressing proliferation and inducing apoptosis. It was suggested that down-regulated BTG3 expression might be considered as a marker for colorectal carcinogenesis. Web(E) Effect of BTG3 kncokdown on cell cycle transition in vitro by flow cytometry. (F) Expression levels of Cyclin D1 and p27 in BTG3-overexpressing and depleting cells by Western blot.
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WebMar 14, 2024 · BTG3 overexpression up- regulated the protein expression of Cyclin E, p16, p27, NF-κB, p38α/β, XIAP, Bcl-2, ATG14 and p53, but down-regulated the mRNA expression of MRP1, BCRP, and mTOR in SW480 and SW620 cells. BTG3 overexpression inhibited tumor growth of SW620 cells by suppressing proliferation and inducing apoptosis. WebMar 17, 2024 · microRNA-106b-5p Promotes Cell Growth and Sensitizes Chemosensitivity to Sorafenib by Targeting the BTG3/Bcl-xL/p27 Signaling Pathway in Hepatocellular …
WebMar 17, 2024 · Mechanistic studies showed that B-cell translocation gene 3 (BTG3), a known antiproliferative protein, was a direct target of miR-106b-5p, whose expression … WebmiR-106b-5p induces sorafenib resistance of HCC cells through BTG3/Bcl-xL/p27. (a) Immunofluorescence staining analysis showed the colocalization of BTG3 and Bcl-xL in MHCC-97L and HCC-LM3 cells. Scale bar represents 15 μm. (b) The co-IP study showing the interaction between BTG3 and Bcl-xL in MHCC-97H cells. IgG was used as a …
WebAug 14, 2015 · BTG3 overexpression enhances the sensitivity of gastric cancer cells to chemotherapeutic agents. exposed to cisplatin (DDP), MG132, paclitaxel, and SAHA, … WebBTG3/ANA/APRO4 has been reported to be a tumor suppressor gene in some malignancies. It constitutes important negative regulatory mechanism for Src-mediated signaling, a negative regulator of the cell cycle and inhibits transcription factor E2F1. We report that BTG3 is downregulated in renal cancer …
WebDec 11, 2024 · B-cell-translocation gene 3 ( BTG3) is a member of the BTG gene family, members of which share a conserved N-terminal domain, but have divergent C-terminal domains 13. The conserved N-terminal ...
WebOct 24, 2011 · BTG3 transfectants showed a higher mRNA expression of p27, Bax, 14-3-3, Caspase-3, Caspase-9, Beclin 1, NF-κB, IL-1, -2, -4, -10 and -17, but a lower mRNA expression of p21, MMP-9 and VEGF than ... pony clothes streetwearWebFeb 21, 2015 · BTG3 overexpression up- regulated the protein expression of Cyclin E, p16, p27, NF-κB, p38α/β, XIAP, Bcl-2, ATG14 and p53, but down-regulated the mRNA expression of MRP1, BCRP, and mTOR in ... pony cleaning gameWebSep 16, 2024 · B cell transposition gene 3 (BTG3) is reported to be a tumor suppressor and suppresses proliferation and cell cycle progression. This study aims to analyze the … pony club area 16Web小鼠降钙素基因相关肽 elisa试剂盒，降钙素基因相关肽检测，检测精度高重复性好的试剂盒。买elisa试剂盒，Z担心没有保障，浪费财力物力和精力。 shape of you id robloxWebBTG3 overexpression markedly downregulated Cyclin D1 and Cyclin E1 levels, whereas elevated p27. Overexpression of BTG3 arrested the cell cycle at G1 phase, which was abrogated by p27 silencing. Furthermore, migration, invasion and EMT of SW480 cells were significantly suppressed by BTG3 overexpression. pony clothes for girlsWebp27kip1 (p27) is a member of the universal cyclin-dependent kinase inhibitor (CDKI) family. p27 expression is regulated by cell contact inhibition and by specific growth factors, such as transforming growth factor (TGF)-beta. Since the cloning of the p27 gene in 1994, a host of other functions have … shape of you id for robloxWebDownload Table BTG3 expression in colorectal carcinogenesis and subsequent progression from publication: The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of ... pony club adelaide hills